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coenzyme A

   Also found in: Medical, Acronyms, Encyclopedia, Wikipedia 0.03 sec.
coenzyme A
n. Abbr. CoA
A coenzyme present in all living cells that functions as an acyl group carrier and is necessary for fatty acid synthesis and oxidation, pyruvate oxidation, and other acetylation reactions.

coenzyme A
n
(Life Sciences & Allied Applications / Biochemistry) a constituent of biological cells that functions as the agent of acylation in metabolic reactions Abbreviation CoA

coenzyme A
A coenzyme that consists of a nucleotide linked to pantothenic acid (part of the vitamin B complex), is present in all living cells, and functions as an acyl group carrier. Coenzyme A is necessary for fatty acid synthesis and oxidation, pyruvate oxidation, and other acetylation reactions. In cellular respiration, each of two acetyl groups derived from the original glucose molecule attaches itself to coenzyme A as acetyl coenzyme A and then enters the Krebs cycle.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.coenzyme A - a coenzyme present in all living cells; essential to metabolism of carbohydrates and fats and some amino acids
coenzyme - a small molecule (not a protein but sometimes a vitamin) essential for the activity of some enzymes


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Vitamin B5 can be converted in the body to Coenzyme A that not only breaks proteins down into individual amino acids, but also takes part in the first part of the Krebs Cycle.
The pyruvate is oxidatively decarboxylated to form acetyl Coenzyme A (Acetyl CoA) which passes through the cycle.
Because coenzyme A acts in conjunction with other enzymes to facilitate reactions in living organisms, the authors believe it may have "acted in this capacity very early in the development of life on Earth.
 
 
 
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