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Related to Cold agglutinin disease: cold antibody


An antibody or other substance that is capable of causing agglutination, as of red blood cells or bacteria.


(Biology) a substance, such as an antibody or a lectin, that causes agglutination of cells or bacteria
[C19: agglutinate + -in]


(əˈglut n ɪn)

an antibody that causes agglutination.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.agglutinin - an antibody that causes agglutination of a specific antigen
antibody - any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response
isoagglutinin - an antibody produced by one individual that causes agglutination of red blood cells in other individuals of the same species
References in periodicals archive ?
Because of its MOA involving the complement system, a mechanism potentially conserved across numerous disease conditions involving the immune system, its potential is also being explored in dozens of investigator-initiated trials for other conditions, including kidney transplantation, macular degeneration, CD59 deficiency, dense deposit disease and C3 nephropathy, and cold agglutinin disease.
Cold Agglutinin Disease is a very, rare, immune mediated condition, in which components of blood agglutinate in the vessels, causing thrombus formation with subsequent loss of blood supply.
Steroids, splenectomy, and plasmapheresis are generally unsuccessful in the treatment of cold agglutinin disease.