C-banding of mitotic metaphase revealed constitutive heterochromatin
blocks (thin C-bands) in the paracentromeric region in most chromosomal elements, with the exception of one small pair of autosomes (thick C-bands).
Approximately 15-20% of this non-coding part of human DNA is constitutive heterochromatin
The researchers looked in detail at the mysterious tightly packed portions of the genome, called constitutive heterochromatin
The constitutive heterochromatin
(C-banding) was performed according to Sumner (1972), with some minor adjustments (Lui et al.
2011), the principal component of the constitutive heterochromatin
regions were observed on the centromeres of chromosomes in all four species by using C-banding.
C-band results showed that all constitutive heterochromatin
was confined to the X chromosome, differing from the pattern observed in Cavia and Galea.
Detection of constitutive heterochromatin
(C-banding) was performed according to Sumner (1972), with some minor modifications.
regions (C-bands) were revealed using the method of Summer (1972), using propidium iodide as a counterstain.
C banding by constitutive heterochromatin
was located in pericentromeric and telomeric position.
Morphological variations of constitutive heterochromatin
are frequently detected during routine cytogenetic analysis.
The latest research for examining constitutive heterochromatin
, pathology-related inclusions and sumoylation are also discussed.