antiglobulin test

(redirected from Coombs test)
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an·ti·glob·u·lin test

n. prueba de la antiglobulina.
References in periodicals archive ?
Tenders are invited for BarMT 92 / 18 monoclonal reagents, concentrates of monoclonal reagents, reagents of the Coombs test, test systems for microbiological studies
The minor blood groups of the mother and baby tested to investigate the etiology of hyperbilirubinemia and positive direct Coombs test were as follows: mother: C(+) c(+) E(-) e(+) Kell (-), baby: C(+) c(+) E(+) e(+) Kell(-).
These tests showed positive antinuclear antibody (1: 1000 granular pattern), anti-Ro (SSA) antibody (2+), anti-La (SSB) antibody (3+), Ro-52 (3+), and direct Coombs test (immunoglobulin G) (4+).
Coombs test both direct and indirect were negative.
ABO hemolytic disease characterizes neonatal jaundice with a positive coombs test against the A or B antigens in babies born to mothers with blood group O.
Raised lactate dehydrogenase and bilirubin levels, in the presence of a negative Coombs test, suggested the presence of non-autoimmune-mediated haemolytic anaemia.
The indirect Coombs test was devised to seek the presence of incomplete antibodies in the patient's serum.
The lactate dehydrogenase (LDH) level was elevated to 1014U/L and direct coombs test (DAT) was repeated and again negative.
Septic screen was negative, coombs test was positive and urine output 200 ml/day (normal 1 L/day).
She was diagnosed with as autoimmune hemolytic anemia (ATHA) based on a high reticulocyte count, positive direct Coombs test, hemoglobinuria, and low haptoglobin level, and received the conventional treatment of prednisone (2 mg/kg in divided doses) and blood transfusions.
1] Rebound hyperbilirubinaemia may occur after cessation of phototherapy, especially if the Coombs test is positive, if the infant was born prematurely, and if the duration of phototherapy was less than 72 hours.
Other possible hemolytic anemia or enzyme deficiencies causes were excluded (negative Coombs test, normal glucose-6-phosphate dehydrogenase enzyme level, normal hemoglobin electrophoresis and bone marrow aspiration).