NASDAQ: GNSA) today announced that an abstract summarizing certain data from its multi-center Phase 2 clinical trial with Arasine(TM) in 116 patients undergoing coronary artery bypass
surgery has been published in the Journal of the American College of Cardiology.
The company's initial therapeutic focus for Anginera is as an adjunct therapy in patients undergoing coronary artery bypass
graft (CABG) surgery.
The study results showed that MC-1 had a statistically significant reduction in the composite of death, non-fatal myocardial infarctions (peak CK-MB greater than or equal to 100ng/ml), and non-fatal strokes versus placebo in patients undergoing coronary artery bypass
Michael's, decided to conduct a meta-analysis of all existing randomized control trials comparing the two procedures- coronary artery bypass
surgery (CABG) and the angioplasty.
Comment: Cardiopulmonary bypass, which occurs during coronary artery bypass
graft surgery, is known to induce oxidative stress and to decrease antioxidant levels.
Conclusion: Off-pump coronary artery bypass
grafting can be performed with good clinical results.
Inclusion criteria: Patients 60 years of age or over undergoing non-urgent coronary artery bypass
graft surgery with or without valve replacement/repair
The majority of coronary artery bypass
grafts in the United States use blood vessels that have been harvested from somewhere else on the patient's body, usually from the legs.
In their study, 35 coronary artery bypass
graft patients underwent neurologic examination, neuropsychologic examination, diffusion-weighted MRI, and magnetic resonance spectroscopy before and after the cardiac procedure (Arch.
Stress experience of spouses of patients having coronary artery bypass
during hospitalization and 6 weeks after discharge.
In addition, female candidates for coronary artery bypass
surgery must confront the stark fact that the operation itself - a risky but potentially lifesaving procedure - puts women in greater jeopardy of death than men.
Stroke Following Coronary Artery Bypass
Surgery-A Case-Control Estimate of the Risk from Carotid Bruits.