Cowhage


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Cow´hage

    (kou´hãj)
n.1.(Bot.) A leguminous climbing plant of the genus Mucuna, having crooked pods covered with sharp hairs, which stick to the fingers, causing intolerable itching. The spiculæ are sometimes used in medicine as a mechanical vermifuge.
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The first study comprised 32 healthy subjects in whom itch was induced with cowhage before and after skin treatment with the strontium gel, a control vehicle, topical 1% hydrocortisone, and topical 2% diphenhydramine (Acta Derm Venereol.
John's wort, changes induction of echinacea, ginkgo, cytochrome P450 garlic, grapefruit, enzymes goldenseal, resveratrol Changes in Increased diuresis Dandelion, yerba mate, elimination or fluid retention stinging nettle, cowhage Pharmacodynamic Supplement has Anticonvulsants: ginkgo interactions either similar or (may lower seizure opposing effects threshold) to target drug Antihypertensives: yohimbe (could increase blood pressure) CNS depressants: valerian (GABA agonist)
Yosipovitch and colleagues induced itch on the ankles, forearms and backs of 18 study participants with cowhage spicules, which come from a type of legume found in tropical areas that are known to cause intense itching.