Creutzfeldt-Jakob disease

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Related to Creutzfeld-Jakob disease: Huntington's disease, mad cow disease

Creutz·feldt-Ja·kob disease

 (kroits′fĕlt-yä′kôp)
n. Abbr. CJD
A fatal degenerative disease of the brain, caused by a prion and marked by progressive dementia and gradual loss of muscle control. Also called Jakob-Creutzfeldt disease.

[After Hans G. Creutzfeld (1883-1964) and Alfons M., Jakob (1884-1931), German psychiatrists.]

Creutzfeldt-Jakob disease

(ˈkrɔɪtsfɛlt ˈjɑːkɒp)
n
(Pathology) pathol a fatal slow-developing disease that affects the central nervous system, characterized by mental deterioration and loss of coordination of the limbs. It is thought to be caused by an abnormal prion protein in the brain
[C20: named after Hans G. Creutzfeldt (1885–1964) and Alfons Jakob (1884–1931), German physicians]

Creutz′feldt-Ja′kob disease`

(ˈkrɔɪts fɛltˈyɑ kɔp)
n.
a fatal degenerative disease of the human brain, thought to be caused by an abnormal, infectious form of cellular prion protein.
[1965–70; after German physicians Hans German. Creutzfeldt (1885–1964) and Alfons Jakob (1884–1931)]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.Creutzfeldt-Jakob disease - rare (usually fatal) brain disease (usually in middle age) caused by an unidentified slow virus; characterized by progressive dementia and gradual loss of muscle control
brain disease, brain disorder, encephalopathy - any disorder or disease of the brain
Translations

Creutzfeldt-Jakob disease

References in periodicals archive ?
dagger]) AFSSA, Agence Francaise de Securite Sanitaire des Aliments National TSE Reference Laboratory, Lyon, France; BHUFA, Biobanco Hospital Universitario Fundacion Alcorcon, Madrid, Spain; CISA, Centro de Investigacion en Sanidad Animal, Madrid, Spain; INRA, French National Institute for Agricultural Research, Nouzilly, France; NIBSC, National Institute for Biologic Standards and Control Creutzfeld-Jakob Disease Resource Centre, South Mimms, Potters Bar, United Kingdom; Roslin, The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom; VLA, Veterinary Laboratory Agency, New Haw.
These non-temporal lesions included basal ganglia hyperintensity plus cortical ribboning determined in 2 patients who were finally diagnosed with Creutzfeld-Jakob disease (CJD), multiple contrast enhanced lesions in 1 patient diagnosed with carcinomatous meningitis, and bilateral periventricular lesions in 1 patient diagnosed with acute disseminating encephalomyelitis (ADEM).
Key words: Creutzfeld-Jakob Disease, Prion disease, Rapidly progressive dementia, CSF protein tau, CSF protein 14-3-3
Like bovine spongiform encephalopathy (BSE) and variant Creutzfeld-Jakob Disease (mad cow disease), kuru is caused by prions in the brain.
Electroencephalography was done and showed moderate encephalopathy of non-specific etiology with no signs of seizures or spikes to suggest Creutzfeld-Jakob disease.
London, March 21 (ANI): It is believed that when vital proteins are misfolded in your body, neurodegenerative disorders such as Alzheimer's, Parkinson, and Creutzfeld-Jakob disease occur.
and Britain died after becoming infected with Creutzfeld-Jakob disease, the degenerative neurological disorder, from a contaminated batch of hGH.
A human TSE, Creutzfeld-Jakob Disease, was first documented in the 1920s.
Surgical instruments used by surgeons for this type of operation were thrown away after each use amid fears of a "theoretical risk" of spreading variant Creutzfeld-Jakob Disease when reusable instruments were used, a top Department of Health advisor told the hearing.
The original text has been revised and rearranged for the second edition, with new sections on global warming, socioeconomic aspects, recent outbreaks that have appeared since publication of the first edition--including severe acute respiratory syndrome (SARS), bovine spongiform encephalopathy (BSE or mad cow disease), new variant Creutzfeld-Jakob disease (CJD), and the increasing spread of HIV infection--and others that may prove significant in the future.
The human form of Mad Cow disease, more formally known as new variant Creutzfeld-Jakob Disease (nv-CJD), is a chronic and incurable deterioration of the central nervous system, one of a larger class of diseases called transmissible spongiform encephalopathies (TSEs).
The Government announced last month that experts had advised a ban on blood donation on anyone who had had a transfusion since January 1980 because of a "slight risk" of the transmission of variant Creutzfeld-Jakob disease (vCJD).