Creutzfeldt-Jakob disease

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Related to Creutzfeldt-Jacob disease: mad cow disease, Huntington's disease

Creutz·feldt-Ja·kob disease

n. Abbr. CJD
A fatal degenerative disease of the brain, caused by a prion and marked by progressive dementia and gradual loss of muscle control. Also called Jakob-Creutzfeldt disease.

[After Hans G. Creutzfeld (1883-1964) and Alfons M., Jakob (1884-1931), German psychiatrists.]

Creutzfeldt-Jakob disease

(ˈkrɔɪtsfɛlt ˈjɑːkɒp)
(Pathology) pathol a fatal slow-developing disease that affects the central nervous system, characterized by mental deterioration and loss of coordination of the limbs. It is thought to be caused by an abnormal prion protein in the brain
[C20: named after Hans G. Creutzfeldt (1885–1964) and Alfons Jakob (1884–1931), German physicians]

Creutz′feldt-Ja′kob disease`

(ˈkrɔɪts fɛltˈyɑ kɔp)
a fatal degenerative disease of the human brain, thought to be caused by an abnormal, infectious form of cellular prion protein.
[1965–70; after German physicians Hans German. Creutzfeldt (1885–1964) and Alfons Jakob (1884–1931)]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.Creutzfeldt-Jakob disease - rare (usually fatal) brain disease (usually in middle age) caused by an unidentified slow virus; characterized by progressive dementia and gradual loss of muscle control
brain disease, brain disorder, encephalopathy - any disorder or disease of the brain

Creutzfeldt-Jakob disease

References in periodicals archive ?
Each chapter opens with a theoretical introduction to issues such as overcoming ethical dilemmas, assisted suicide and mental health, and Creutzfeldt-Jacob disease and palliative care, and then details practical applications of these ideas.
Transmissible spongiform encephalopathies (TSE) or prion diseases are a group of neurodegenerative afflictions which include Creutzfeldt-Jacob disease (CJD) in humans, scrapie in sheep and goats, and bovine spongi form encephalopathie (BSE) in cattle.
Washington, May 10 (ANI): In a major breakthrough, scientists from the National Institute of Allergy and Infectious Diseases have developed a method-10,000 times more sensitive than other methods-to detect variant Creutzfeldt-Jacob disease (vCJD) in blood plasma.
Humans who consume BSE-infected meat can contract its human form, variant Creutzfeldt-Jacob disease or CJD of which there were 195 confirmed cases by July 2007: 163 in the UK, 22 in France, four in Ireland, two in the Netherlands, two in Portugal, one in Italy and one in Spain.
They believe that, in the right doses, luteolin could be used to treat patients with a range of brain conditions, including Alzheimer's and Creutzfeldt-Jacob Disease (CJD).
Source of variant Creutzfeldt-Jacob disease outside United Kingdom.
The chapters describe diseases such as Creutzfeldt-Jacob disease, kuru, mad cow disease (BSE), chronic wasting disease and scrapie, highlighting their biochemical, molecular biological, genetic, and clinical aspects.
In addition, it found patients had been exposed to the risk of infection with HIV, Creutzfeldt-Jacob Disease (CJD), acute allergic reactions, rejection reactions or malignant tumours.
While the method poses some safety concerns, the researchers believe that it paves the way for preventing prion-triggered diseases, including mad cow disease, formally known as bovine spongiform encephalopathy, and its human form, Creutzfeldt-Jacob disease.