Crocin


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Cro´cin


n.1.(Chem.) The coloring matter of Chinese yellow pods, the fruit of Gardenia grandiflora.
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Protective effect of crocin against cerebral ischemia in a dose-dependent manner in a rat model of ischemic stroke.
Anti-hyperglycemic effects of saffron and its active constituents, crocin and safranal, in alloxan-induced diabetic rats.
Similares efectos se constataron cuando se empleo la catalasa en espermatozoides humanos (46) , porcinos (57) , bovinos (24) y ciervos (23) y de igual forma, el trolox en equinos (64) y caprinos (63) , la taurina en bovinos (20,) (54) y caprinos (6) y finalmente, los carotenoides como la luteina y crocin en semen de porcinos y caprinos (25,) (42) .
jasminoides extracts and their main active phytoconstituents geniposide, genipin, crocin, crocetin have been reported for a wide range of pharmacological activities such as anti-hyperglycemic, anti-atherosclerotic, anti-inflammatory, anti-arthritis, and anti-cancer etc.
Its major constituents include crocin, crocetin, safranal can also be classified as antioxidants and share structural similarities with other antioxidants, such as zeaxanthin.
According to the reaction mechanism these assays are divided into two broad categories: Hydrogen atom transfer assay (HAT) such as inhibition of induced LDL auto-oxidation, oxygen radical absorbance capacity (ORAC), total radical trapping antioxidant parameter (TRAP), crocin bleaching assays and electron transfer assay (ETA) that includes the TPC assay by the Folin reagent, Trolox equivalence antioxidant capacity (TEAC), ferric ion (Fe3+) reducing antioxidant power (FRAP), "total antioxidant potential" assay where Cu(II) complex captures electrons, and DPPH assay.
Protective effect of crocin on diazinon induced vascular toxicity in subchronic exposure in rat aorta ex-vivo.
Preventive effect of crocin of Crocus sativus on hemodynamic, biochemical, histopathological and ultrastuctural alterations in isoproterenol-induced cardiotoxicity in rats.
Drugs which were taken up on for consideration in the plea included Aceproxyvon, Viscodyne and Viscodyne- D of Wockhardt, Crocin Cold and Flu Max of Glaxo and Grilinctus syrup of Griffon.
Additional methods commonly used include TRAP (Total Reactive Antioxidant Potential), FRAP (Ferric Reducing Ability of Plasma) and bleaching of crocin (from saffron extract), he added.
Anethole, estragole, methylchavicol, apiin, apigenin, myristin, limonene, cineole, safranal, crocin, and picrocrocin (52).