cytochalasin

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cytochalasin

(ˌsaɪtəʊkəˈleɪsɪn; ˌsaɪtəˈkæləsɪn)
n
any of a group of metabolites derived from fungus that interfere with cell processes
References in periodicals archive ?
Actions of cytochalasins on the organization of actin filaments and microtubules in a neuronal growth cone.
The cytochalasins are a group of toxic fungal metabolites which show marked cytotoxic effects on mammalian cells in tissue culture.
Cytochalasins and Phytotoxins from the fungus Xylaria obovata.
1973); by the fertilization modifications of microfilament distribution, particularly in fertilization cones (Longo, 1978b, 1980; Tilney and Jaffe, 1980; Schatten and Schatten, 1980; Cline and Schatten, 1986); and by the blockage of fertilization by the inhibition of microfilament polymerization using cytochalasins (Gould-Somero et al.
Four cytochalasins, termed phomachalasins A-D (11-14), were isolated and characterised as three closely related 26- oxa[16] and one new[15] cytochalasan.
The cytochalasins are a group of toxic fungal metabolites which exhibited a broad spectrum of biological activity including antibiotic and antitumor activity (Katagiri and Matsura 1971), inhibition of HIV-1 protease (Wells et al.
Apoptosis induction in HCT116 cells by cytochalasins isolated from the fungus Daldinia vernicosa.
2004) isolated two phytotoxic compounds namely cytochalasin B and dihydrocytochalasins from culture filtrates of D.
Early studies also demonstrated that growth cone motility depends on actin filament assembly (Yamada and Wessells, 1973), and a critical role for actin assembly in axonal guidance emerged when axons in the developing grasshopper nervous system were shown to lose all path-finding capabilities upon treatment with cytochalasin (Bentley and Toroion-Raymond, 1986).