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cyclophosphamide
(redirected from Cytoxan)

   Also found in: Medical, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
cy·clo·phos·pha·mide  (skl-fsf-md)
n.
A highly toxic, immunosuppressive, antineoplastic drug, C7H15Cl2N2P, used in the treatment of Hodgkin's disease, lymphoma, and certain other forms of cancer, such as leukemia and breast cancer.

cyclophosphamide [ˌsaɪkləʊˈfɒsfəˌmaɪd]
n
(Medicine / Pharmacology) an alkylating agent used in the treatment of leukaemia and lymphomas
[from cyclo- + phosph(orus) + amide]


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A fifth possibility is Cytoxan (or cyclophosphamide), which some studies show to be effective and others indicate has no Clear benefit.
In a study involving 388 women with ovarian cancer, tumor tissue shrank or disappeared in 73 percent of women taking taxol and cisplatin, compared with 59 percent of those receiving cytoxan and cisplatin, reports William P.
Off-label use of rituximab (Biogen Idec/Genentech's Rituxan), currently in Phase III for CLL, has had significant success in combination with fludarabine and cyclophosphamide (Bristol-Myers Squibb's Cytoxan, Baxter's Endoxan/Endoxana, Pfizer's Neosar/Cyclostin, generics) in previously untreated patients, and we expect its adoption to increase when rituximab is approved.
 
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