Identification of metabolites of the antitumor agent D-limonene
capable of inhibiting protein isoprenylation and cell growth.
The sorbent bed breakthrough curve described by the model matched well with corresponding experimental data for the VOCs tested, including toluene, decane, hexane, butanone, iso-butonal, tetracholorothylene, and d-limonene
under relatively high concentration levels (ppm).
Crowell PL, Chang RR, Ren Z, Elson CE, Gould MN (1991) Selective inhibition of isoprenylation of 21-26-kDa proteins by the anticarcinogen d-Limonene
and its metabolites.
Compounds associated with consumer product use include p-dichlorobenzene (moth cakes, room air fresheners, toilet bowl deodorizers), chloroform (chlorinated water), and the fragrances [alpha]- and [beta]-pinene and d-limonene
(cleaning products, room fresheners) (Wallace 1991a, 1991b).
Key words: Lippia alba, citral, [beta]-myrcene, d-limonene
, central effects
It perfomis similarly to d-Limonene
but is biodegradable, a non-irritant, has low odor, and complies with SCAQMD regulations.
The increases were taken to offset continued increases in commodity costs, including D-limonene
, which is used in a broad range of citrus-based cleaning and plumbing products, the company said.
This issue is also illustrated by the near, but imperfect, "consensus" on the [alpha]2[mu]-globulin mechanism of male rat renal carcinogenesis induced by d-limonene
and its lack of relevance for humans.
025 (11) [ILLUSTRATION OMITTED] TMTU Trimethylthiourea [5989-27-5] Gav 75 (17) [ILLUSTRATION OMITTED] 300 LIM d-Limonene
DOSE LEVELS (a) Rats Mice CAS No.
Applications: non-bleach based hard surface cleaners, car and truck washes, pressure wash cleaners, general purpose degreasers, d-limonene
and pine oil based degreasers, acidic lime scale removers.
Limonene was introduced into the inner chamber either by the evaporation of reagent-grade d-limonene
or by inserting a lemon-scented, solid air freshener.