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DNA methylation |
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Therefore, SmaI macrorestriction patterns generate only 1 large fragment because of protection by a novel DNA methylation enzyme (12). The extent of this DNA methylation was similar in endodermal, mesodermal, and ectodermal tissues, indicating that genistein acts during early embryonic development. Abnormal DNA methylation is often found on DNA from cancerous cells and is believed to impact a tumor's sensitivity to chemotherapeutic drugs. |
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