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DNA methylation

   Also found in: Wikipedia 0.02 sec.
DNA methylation  (mth-lshn)
The modification of a strand of DNA after it is replicated, in which a methyl (CH3) group is added to any cytosine molecule that stands directly before a guanine molecule in the same chain. Since methylation of cytosines in particular regions of a gene can cause that gene's suppression, DNA methylation is one of the methods used to regulate the expression of genes.
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The head-to-head comparison brought to light a novel DNA methylation pattern unique to stem cells, which may explain how stem cells establish and maintain their pluripotent state, the researchers say.
The first complete human epigenome mapped by Asian News International
Scientists in medicine and nutrition from the US and UK explore the interrelationships between nutrition and epigenetic phenomena, including DNA methylation, histone modifications, and chromatin remodeling; the role of epigenetics in embryonic development, aging, inflammation, and the development of cancer; and how nutrients affect and modulate these physiologic and pathologic processes.
Nutrients and epigenetics by SciTech Book News
[ILLUSTRATION OMITTED] The Johns Hopkins group has now shown that DNA methylation is more common at what they call "CpG island shores" instead of at the CpG islands that most researchers have focused on.
Epigenetics: from islands to the shores: tissue-specific DNA tagging ... by Saey, Tina Hesman / Science News
 
 
 
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