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DNA methylation

   Also found in: Wikipedia 0.06 sec.
DNA methylation  (mth-lshn)
The modification of a strand of DNA after it is replicated, in which a methyl (CH3) group is added to any cytosine molecule that stands directly before a guanine molecule in the same chain. Since methylation of cytosines in particular regions of a gene can cause that gene's suppression, DNA methylation is one of the methods used to regulate the expression of genes.
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Therefore, SmaI macrorestriction patterns generate only 1 large fragment because of protection by a novel DNA methylation enzyme (12).
Methicillin-resistant Staphylococcus aureus ST398 in humans and ... by Cuny, Christiane / Emerging Infectious Diseases
The extent of this DNA methylation was similar in endodermal, mesodermal, and ectodermal tissues, indicating that genistein acts during early embryonic development.
Maternal genistein alters coat color and protects [A.sup.vy] mouse ... by Jirtle, Randy L. / Environmental Health Perspectives
Abnormal DNA methylation is often found on DNA from cancerous cells and is believed to impact a tumor's sensitivity to chemotherapeutic drugs.
ORION/UNIVERSITY OF GLASGOW TO IDENTIFY EPIGENETIC BIOMARKERS by Worldwide Biotech
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