darunavir


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Related to darunavir: Raltegravir
Translations

darunavir

n darunavir m
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References in periodicals archive ?
Cipla in early morning trade after getting tentative approval from the US Food and Drug Administration for HIV drug, Darunavir hydrate (75-800 mg).
In SA, atazanavir is routinely available for children > 12 years of age and darunavir on a special application basis for children > 3 years old.
High viral load, previous fosamprenavir use and more recent HIV diagnosis correlate with darunavir failure in salvage therapy in Sao Paulo, Brazil.
Findings from the study demonstrated that the single tablet regimen D/C/F/TAF provided effective and durable viral suppression, meaning most patients achieved an undetectable viral load, whilst offering the high genetic barrier to resistance of darunavir, for ART-naive HIV-1-infected patients.
Atazanavir (Reyataz[R]), darunavir (Prezista[R]), fosamprenavir (Lexiva[R], Telzir[R]), indinavir (Crixivan[R]), lopinavir and ritonavir combination (Kaletra[R]), nelfinavir (Viracept[R]), saquinavir (Invirase[R], Fortovase[R]), and tipranavir (Aptivus[R]) are PIs (AIDSinfo, 2016; FDA, 2016).
The preferred regimens for starting treatment in the major international treatment guidelines have gradually moved towards an NRTI backbone of tenofovir disoproxil fumarate/ emtricitabine (TDF/FTC), tenofovir alafenamide/FTC (TAF/FTC) or abacavir/lamivudine (ABC/3TC) plus either the protease inhibitor (PI) darunavir (DRV) boosted by either ritonavir (r) or cobicistat (c), or the integrase inhibitors raltegravir (RAL), elvitegravir (ELV) or dolutegravir (DTG) or the non-nucleoside reverse transcriptase inhibitors rilpivirine (RPV) or efavirenz (EFV)--see EACS Guidelines.
An investigational single-tablet regimen containing darunavir is effective and well tolerated, US-based health care company Johnson and Johnson's (NYSE: JNJ) Janssen-Cilag International NV (Janssen) subsidiary.
25) Even when boosted with ritonavir, the currently favored PIs darunavir (39,40) and atazanavir (40,41) upset lipids less than previous PIs.
PI-based regimen Darunavir (Prezista) and ritonavir (Norvir) plus tenofovir disoproxil fumarate/emtricitabine (Truvada).
All subjects were on antiretroviral regimens based upon either darunavir (Prezista), atazanavir (Reyataz), raltegravir (Isentress), or dolutegravir (Tivicay).
J&J says that this policy enables the development of and access to new pediatric products of darunavir in about 130 low- and middle-income countries that are home to 99.
The company offers protease inhibitors such as ritonavir, darunavir, saquinavir, amprenavir, lopinavir, atazanavir, indinavir and tipranavir.