Deflux


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De`flux´


n.1.Downward flow.
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The product portfolio today contains: RESTYLANE, for the correction of wrinkles, lip shaping and for facial contouring; DUROLANE, for the treatment of osteoarthritis of the hip and knee joints; DEFLUX, for the treatment of vesicoureteral reflux (a malformation of the urinary bladder) in children and ZUIDEX, for the treatment of stress urinary incontinence in women.
The study was funded by Q-Med AB, a company that makes Deflux (dextranomer/hyaluronic acid copolymer), one of the options in bulking agents used for endoscopic treatment of VUR.
Over the last decades, dextranomer hyaluronic acid (Dx/HA, Deflux, Oceana Therapeutics Ltd, Dublin, Ireland) has become the most commonly used bulking agent worldwide.
Salix) announced that the Center for Devices and Radiological Health (CDRH) of the Food and Drug Administration (FDA) has approved Deflux premarket approval (PMA) supplement, which requested approval of labeling changes to add two additional techniques for injection, a single intra-ureteric injection (HIT procedure) and a double (proximal and distal) intra-ureteric injection (Double-HIT procedure).
In April 2011, following an unsuccessful deflux injection, a Monti revision procedure was completed utilizing a modified spiral Casale over a 12 Fr catheter.
375 g, GIAZO (TM)(balsalazide disodium) tablets, COLAZAL (balsalazide disodium) Capsule, METOZOLV ODT (metoclopramide HCl), RELISTOR (methylnaltrexone bromide) Subcutaneous Injection, FULYZAQ (TM)(crofelemer) delayed-release tablets, SOLESTA, DEFLUX, PEPCID (famotidine) for Oral Suspension, DIURIL (Chlorothiazide) Oral Suspension, AZASAN (Azathioprine) Tablets, USP, 75/100 mg, ANUSOL-HC 2.
He is also a member of an Advisory Board for Salix, for the injection material, Deflux.
We also broadened our sights to pursue international product opportunities, and as early as mid-2009, within a year of start-up, Oceana was generating a revenue stream through the worldwide sales of Deflux.
Side effects associated with Deflux include UTI, ureteral dilatation, and nausea/vomiting/abdominal pain.
DEFLUX is the only FDA-approved alternative to major ureteral reimplantation surgery for the treatment of children with vesicoureteral reflux (VUR) grades II-IV.
Deflux, Solesta and Durolane are other products improving patients' health in the corrective field.
After treatment with DEFLUX, 13 percent of patients (n=13) had recurrent UTIs compared to 75 percent (n=75) before DEFLUX treatment, with a five-fold reduction in the incidence of UTIs per year (0.