In higher organisms, they fall into only two categories: xanthine dehydrogenases
are involved in metabolic pathways; sulfite oxidases catalyse a small but important set of reactions involved in brain development.
Possible role of liver cytosolic and mitochondrial aldehyde dehydrogenases
in acetaldehyde metabolism.
Expression of lactate dehydrogenases
A and B during chicken spermatogenesis: Characterization of testis specific transcripts.
The agreement grants DSM rights to c-LEcta's proprietary alcohol dehydrogenases
for enzyme screening programs and development of sustainable manufacturing routes for manufacturing of pharmaceutical active ingredients and intermediates.
(11beta-HSD) are microsomal enzymes that catalyze the conversion of active glucocorticoids (GC) to their inactive 11-dehydro products and vice versa.
Therefore, we suspect that endogenous dehydrogenases
and substrates other than LDH and lactate may be implicated in NADH production, leading to the false ethanol increases.
The papers represent the latest research in aldehyde dehydrogenases
(including such topics as unexpected encounters in simulations f the ALDH mechanism and detoxification of chloroacetaldehyde by human class-9 aldehyde dehydrogenase
), alcohol dehydrogenases
(including functional roles of alcohol dehydrogenases
in human ethanol metabolism and the diversity of beta-hydroxyacid dehydrogenases
in plants), carbonyl reductases (including life without aldose reductase, lead optimization in the design of aldose reductase inhibitors and characterizations of a number of test animal organs).
Genes encoding enzymes known as alcohol dehydrogenases
can be readily identified among diverse organisms, including humans, bacteria, plants, and fungi.
catalyzed) by enzymes known as alcohol dehydrogenases
Thus, systems and methods are provided for the recombinant expression of secoisolariciresinol dehydrogenases
that may be used to facilitate the production, isolation and purification of significant quantities of recombinant secoisolariciresinol dehydrogenase
for subsequent use, to obtain expression or enhanced expression of secoisolariciresinol dehydrogenase
in plants in order to enhance, or otherwise alter, lignan biosynthesis, or may be employed for the regulation or expression of secoisolariciresinol dehydrogenase
Based on published reports on retinoic acid metabolism, the model postulated that dietary vitamin A (retinol) is converted first to retinal and then to retinoic acid by alcohol dehydrogenases
and, possibly, by cytochrome P450 enzymes.
Routine blood tests were within normal ranges but asparate aminotransferase (53 IU; normal <45), creatine phosphokinases (140, normal <120), and lactate dehydrogenases
(890, normal <620) were elevated.