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denature
(redirected from denaturation)

   Also found in: Medical, Legal, Encyclopedia, Wikipedia 0.02 sec.
de·na·ture  (d-nchr)
tr.v. de·na·tured, de·na·tur·ing, de·na·tures
1. To change the nature or natural qualities of.
2. To render unfit to eat or drink without destroying usefulness in other applications, especially to add methanol to (ethyl alcohol).
3. Biochemistry
a. To cause the tertiary structure of (a protein) to unfold, as with heat, alkali, or acid, so that some of its original properties, especially its biological activity, are diminished or eliminated.
b. To cause the paired strands of (double-stranded DNA) to separate into individual single strands.
4. Physics To add nonfissionable matter to (fissionable material) so as to prevent use in an atomic weapon.

de·natur·ant n.
de·natur·ation n.

denature [diːˈneɪtʃə], denaturize, denaturise [diːˈneɪtʃəˌraɪz]
vb (tr)
1. to change the nature of
2. (Chemistry) to change (a protein) by chemical or physical means, such as the action of acid or heat, to cause loss of solubility, biological activity, etc.
3. (Chemistry) to render (something, such as ethanol) unfit for consumption by adding nauseous substances
4. (Physics / Nuclear Physics) to render (fissile material) unfit for use in nuclear weapons by addition of an isotope
denaturant  n
denaturation  n

denature  (d-nchr)
1. To cause the tertiary structure of a protein to unfold, as with heat, alkali, or acid, so that some of its original properties, especially its biological activity, are diminished or eliminated.
2. To cause the paired strands of DNA to separate into individual strands.
ThesaurusLegend:  Synonyms Related Words Antonyms
Verb1.denature - add nonfissionable material to (fissionable material) so as to make unsuitable for use in an atomic bomb
alter, change, modify - cause to change; make different; cause a transformation; "The advent of the automobile may have altered the growth pattern of the city"; "The discussion has changed my thinking about the issue"
2.denature - modify (as a native protein) especially by heat, acid, alkali, or ultraviolet radiation so that all of the original properties are removed or diminished
alter, change, modify - cause to change; make different; cause a transformation; "The advent of the automobile may have altered the growth pattern of the city"; "The discussion has changed my thinking about the issue"
3.denature - make (alcohol) unfit for drinking without impairing usefulness for other purposes
alter, change, modify - cause to change; make different; cause a transformation; "The advent of the automobile may have altered the growth pattern of the city"; "The discussion has changed my thinking about the issue"
Translations
denature
vtdenaturieren; (= make unfit for eating, drinking also)ungenießbar machen


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The product has no high temperature denaturation step or RNase solutions, and labware requirements, overnight hybridization and stringent wash conditions are eliminated.
Before we implement this new technology, we need to understand the mechanism and kinetics of pressure-induced degradation, denaturation, activation and inactivation of several food compounds, such as microorganisms, enzymes and nutrients, and the way in which degradation, denaturation and the like are influenced by other parameters, such as temperature and pH.
Parasite DNA was amplified after an initial denaturation at 95[degrees]C for 15 min; 43 cycles of denaturation at 95[degrees]C for 45 s and annealing at 60[degrees]C for 90 sec; and a final extension at 72[degrees]C for 5 min in an i-Q thermocycler (Bio-Rad, Hercules, CA, USA).
 
 
 
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