deprenyl


Also found in: Medical, Wikipedia.
Related to deprenyl: L-deprenyl, Hydergine

deprenyl

(ˈdɛprəˌnɪl)
n
a drug used to treat senile dementia, Parkinson's disease, Alzheimer's disease, and depression, by acting as a monoamine oxidase inhibitor
References in periodicals archive ?
Impact of sustained deprenyl (selegiline) in levodopa-treated Parkinson's disease: a randomized placebo-controlled extension of the deprenyl and tocopherol antioxidative therapy of parkinsonism trial.
Chronic (-) deprenyl administration increases dendritic arborization in CA3 neurons of hippocampus and AChE activity in specific regions of the primate brain.
For this study, the team used the tracer molecules PIB, Deprenyl and FDG to study the amount of amyloid plaques, inflammatory changes in the form of astrocyte activation, astrocytes being the most common type of glial (supporting) cell in the brain.
In the 1980s-1990s, published studies in Europe showed remarkable life span increases in animals given a drug called deprenyl.
Acuna-Castroviejo, "Synergistic effects of melatonin and deprenyl against MPTP-induced mitochondrial damage and DA depletion," Neurobiology of Aging, vol.
1993, Chronic Treatment Of Deprenyl Prolongs The Life Span Of Male Fischer 344 Rats.
Deprenyl induces activities of both superoxide dismutase and catalase but not glutathione peroxidase in the striatum of young male rats.
He previously served as president and chief executive officer of Deprenyl Animal Health Inc.
They conducted a survey study of vitamin D status in stored blood samples from patients with PD who were enrolled in the placebo group of the Deprenyl and Tocopherol Antioxidative Therapy of Parkinsonism (DATATOP) trial.
The Deprenyl and Tocopherol Antioxidative Therapy of Parkinsonism (DATATOP) study was designed to investigate the potential for selegiline to modify the disease course in early PD.
Increased effectiveness of tacrine by deprenyl co-treatment in rats: EEG and behavioural evidence.