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Dereplication

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De`rep`li`ca´tion
n.1.(Biochem.) the process of testing samples of mixtures which are active in a screening process, so as to recognize and eliminate from consideration those active substances already studied; - a stage subsequent to the preliminary screening in the process of discovery of new pharmacologically active substances in mixtures of natural products; - also called counterscreening. See screening.
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With new case studies and illustrations, updated/new material on aspects of bioactive natural product research treat topics including chemical extraction, nuclear magnetic resonance (NMR)-based structure determination, liquid chromatography linked with mass spectrometry and NMR spectroscopy, dereplication approaches, and novel bioassay development.
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