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deoxycorticosterone
(redirected from Desoxycorticosterone)

   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
de·ox·y·cor·ti·cos·ter·one  (d-ks-kôrt-kst-rn)
n.
A steroid hormone, C21H30O3, secreted by the adrenal cortex or produced synthetically and formerly used to treat adrenal insufficiency.

deoxycorticosterone [diːˌɒksɪˌkɔːtɪkəʊˈstɪərəʊn], deoxycortone [diːˌɒksɪˈkɔːtəʊn]
n
(Life Sciences & Allied Applications / Biochemistry) a corticosteroid hormone important in maintaining sodium and water balance in the body


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In a basic physiologic study that looked at isolated aortas from both normotensive and desoxycorticosterone acetate (DOCA)-salt hypertensive rats, it was found that "changes in extracellular magnesium concentration differentially alter endothelin-1-induced contraction in aortae from normotensive and hypertensive rats, possibly by interfering with calcium utilization during contraction.
Clinical investigation on the use of CoQ for treatment of hypertension began when Igarashi et al (19) reported that CoQ reduced elevated blood pressure in unilaterally nephrectomized rats treated with desoxycorticosterone and saline.
 
 
 
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