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 (dĕs-vĕn′lə-făk′sēn, -sĭn)
A drug of the SNRI class, C16H25NO2, used to treat depression.

[des(methyl)-, having a methyl group removed (from des-, variant of de-) + venlafaxine.]


n desvenlafaxina
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The Top 5 most likely to cause somnolence, compared with placebo, are fluvoxamine, mirtazapine, reboxetine, paroxetine, and desvenlafaxine.
Tenders are invited for Tab Desvenlafaxine 50 Mg In Strip Packing
4) Serotonin and Norepinephrine Reuptake Inhibitors (SNRis): They include Duloxetine (Cymbalta), Venlafaxine (Effexor) and Desvenlafaxine (Pristiq).
Venlafaxine is a "prodrug" converted to the active drug Odesmethylvenlafaxine (desvenlafaxine) by this enzyme, so serum concentrations of both venlafaxine and desvenlafaxine were measured and compared to predicted metabolic status on the basis of 2D6 genotyping.
In fact, buproprion and other common antidepressants also act on CYP2D6, limiting the therapeutic arsenal of treatment of depression in these patients mainly to venlafaxine and desvenlafaxine (48).
Eight weeks after she switched to desvenlafaxine [Pristiq], her PHG-9 improved to a 5.
Eighteen drugs are in Phase III development in the US including two GABA receptor agonists pregabalin (Pfizer) and gabapentin GR (Depomed); a sodium channel antagonist mexiletine (Boehringer Ingelheim); three glutamate / NMDA antagonists ketamine intranasal (Javelin), a dextromethorphan/quinidine combination (Avanir), and NP-1 (EpiCept/Epitome); two serotonin/norepinephrine reuptake inhibitors desvenlafaxine (Wyeth), and paroxetine (GSK/Novo Nordisk); an alpha-2 adrenergic receptor antagonist/norepinehrine reuptake inhibitor reboxetine (Pfizer); an opioid receptor agonist/norepinephrine reuptake inhibitor tapentadol (Ortho-McNeil); a dopamine receptor agonist sodium oxybate (Jazz), and a neuromuscular blocking agent botulinum toxin A (Allergan).
Treatment with desvenlafaxine succinate, an experimental nonhormonal therapy, continues to reduce the frequency and severity of moderate to severe hot flashes out to 26 weeks.
Products containing desvenlafaxine and products containing venlafaxine should not be used concomitantly with PRISTIQ.
That list includes vilazodone, desvenlafaxine, levomilnacipran, vortioxetine, as well as the less-traditional choices of I-methylfolate and ketamine.
Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE), today provided an update on its global strategy for desvenlafaxine for the treatment of major depressive disorder (MDD) in adults.
The manufacturer of desvenlafaxine will conduct a 1-year study to resolve cardiovascular and hepatic safety concerns raised by the Food and Drug Administration in an "approvable" letter for the serotonin-norepinephrine reuptake inhibitor, which is under review as a treatment for menopausal hot flashes and night sweats.