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A mild narcotic analgesic drug, C22H29NO2, used in its hydrochloride form and chemically related to methadone. It was withdrawn from use in the United States in 2010 because of its association with abnormal heart rhythms.

[prop(ionate) + oxy- + -phene (alteration of phenyl).]


(Pharmacology) a mildly narcotic drug used to treat pain


(proʊˈpɒk səˌfin)

a nonnarcotic analgesic, C22H29NO2.
[1950–55; prop (ionate) + oxy-2 + (di) phen (yl)]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.propoxyphene - a mildly narcotic analgesic drug (trade name Darvon) related to methadone but less addictive
analgesic, anodyne, pain pill, painkiller - a medicine used to relieve pain
References in periodicals archive ?
CO-PROXAMOL Co-proxamol is used for mild to moderate pain relief is a combination of two active ingredients, dextropropoxyphene and paracetamol, which is typically included as a lower 350mg dose compared with the standard 500mg dose of paracetamol when taken alone.
It should be noted that although much media attention has been given to the potential toxicity of dextropropoxyphene in overdose, and although it has recently been withdrawn from the market in SA, this study revealed that dextropropoxyphene was very seldom used for intentional overdose and no fatalities were reported.
Islamabad, June 22 ( ANI ): Records from Pakistan's devolved federal health ministry indicate that the country's prime ministerial candidate Makhdoom Shahabuddin, during his tenure as health minister, also allowed Danas Pharmaceutical to import 5,000 kg of dextropropoxyphene, a controlled substance used in the manufacture of the medical drug darvon, from India in 2010.
Prosecutors had accused the 47-year-old defendant of possessing 191 Dextropropoxyphene (a sedative) for peddling purposes.
Dextropropoxyphene is present in the following medicines: Distalgesic, Doloxene, Doloxene Co-65, Doxyfene, Lentogesic and Synap Forte, which are used to treat pain.
Nor was tramadol superior to the agents it was compared with in the 4 other active-controlled trials--dihydrocodeine, (14) dextropropoxyphene, (15) pentazocine, (16) and diclofenac (17)--in reducing pain intensity.
ISLAMABAD, January 12, 2011 (Frontier Star): Health ministry has banned usage; manufacturing and sale of narcotics drug Dextropropoxyphene (DDP) in the country but no ban has been slapped on Ephedrine and Pseudo Ephedrine which act as major source in manufacturing narcotics.
The withdrawal is based on all available data, including data from a new study that evaluated the effects of increasing doses of dextropropoxyphene on the heart, Paladin added.
THE PHARMACEUTICAL services have ordered that all medicines containing the chemical dextropropoxyphene are to be withdrawn from the market by the end of the year.
The present study therefore aims to explore the genotoxic potential of some commonly used opioids like codeine, dextromethorphan and dextropropoxyphene in swiss albino mice.
For example, the association of weak opioids, such as dextropropoxyphene, to acetaminophen does not significantly increase pain relief with respect to acetaminophen alone (Li Wan Po and Zhang 1997).
The prevalence of hyperhidrosis in patients with spinal cord injuries and evaluation of the effect of dextropropoxyphene hydrochloride in therapy.