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diethylstilbestrol

   Also found in: Medical, Financial, Acronyms, Encyclopedia, Wikipedia, Hutchinson 0.01 sec.
di·eth·yl·stil·bes·trol  (d-thl-stl-bstrôl, -trl)
n.
A synthetic nonsteroidal substance, C18H20O2, having estrogenic properties and used in the treatment of prostatic cancer. It was once used to treat menstrual disorders and to prevent miscarriage but is no longer prescribed for these cases because of the occurrence of reproductive abnormalities and cancers in the offspring of women so treated.

diethylstilbestrol  (d-thl-stl-bstrôl, -trl)
See DES.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.diethylstilbestrol - a potent estrogen used in medicine and in feed for livestock and poultry
estrogen, oestrogen - a general term for female steroid sex hormones that are secreted by the ovary and responsible for typical female sexual characteristics


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Certain risks associated with prenatal exposure to diethylstilbestrol (DES) may be carried over to the next generation, according to results of a study of 463 women whose mothers had been exposed to DES prenatally and 330 whose mothers had not been exposed to the drug.
For example, the genital cancers that were identified in young women, on average 19 years after their prenatal exposure to the drug diethylstilbestrol, were seen in females who had appeared to be completely normal until that time (Herbst et al.
For 1 month, most mice received drinking water laced with uranium or diethylstilbestrol (DES), an estrogen-mimicking drug.
 
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