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Draize test

   Also found in: Medical, Wikipedia 0.11 sec.
Draize test  (drz)
n.
A test to determine the degree to which a substance such as a cosmetic or pharmaceutical irritates human tissues, in which a small amount of the substance is applied directly in the eye of a rabbit, and the rabbit is then monitored.
[After John Henry Draize (1900-1992), American pharmacologist.]


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Even supposedly simple targets for replacement, such as the Draize test for eye irritation, have proved difficult to model in vitro and progress through successful external validation despite major efforts by the European Centre for the Validation of Alternatives (ECVAM), industry trade associations, individual companies, and academia.
Alternatives to toxicity testing in animals: challenges and ... by McNamee, Pauline / Environmental Health Perspectives
One commonly used procedure is the Draize Test, which is used to test household products for harmful chemicals.
Animal Research by Miller, Sarah Rose A. / The Humanist
The irritants depressed metabolism in test cells by amounts that closely parallel Draize test results.
Listening to the breaths of 1,000 cells by Science News
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