Ecgonine


Also found in: Medical, Encyclopedia, Wikipedia.
Related to Ecgonine: Ecgonine benzoate

Ec´go`nine


n.1.(Chem.) A colorless, crystalline, nitrogenous base, obtained by the decomposition of cocaine.
References in periodicals archive ?
Cocaine and its metabolites BZE and ecgonine methyl ester [93], and
Prosecutors charged him with consuming cocaine and benzoyl ecgonine (a metabolite of cocaine).
ii) 5 kilograms or more of a mixture or substance containing a detectable amount of (I) coca leaves, except coca leaves and extracts of coca leaves from which cocaine, ecgonine, and derivatives of ecgonine or their salts have been removed;
Analysis of cocaine, benzoylecgonine, ecgonine methyl ester, ethylcocaine and norcocaine in human urine using HPLC with post-column ion-pair extraction and fluorescence detection.
BChE metabolizes cocaine into ecgonine methyl ester and benzoic acid, which have little toxicity and lack rewarding actions.
Cocaine is extensively metabolized, forming the metabolites benzoylecgonine, ecgonine methyl ester, and ecgonine.
They have now isolated from the microbes an enzyme that splits cocaine into benzoic acid and ecgonine methyl ester.
Lack of validity of the KDI Quik Test drug screen for the detection of benzoyl ecgonine in urine.
Nasdaq:ETOP) (Nasdaq:ETOPW), a specialty pharmaceutical company developing new therapeutics for painful soft tissue injuries and diseases, today announced that the European Patent Office (EPO) has issued a patent based on Entropin's primary composition patent application, "Derivatives of Benzoylecgonine, Ecgonine, And Ecgonidine And Methods Of Preparing and Using the Same.
Simultaneous analysis of ecgonine methyl ester, benzoylecgonine,
5 [micro]g/L LOQs for cocaine, BE, and ecgonine methylester (EME).
COC-AB has been shown to selectively bind cocaine and cocaethyl at much higher affinity than benzoyl ecgonine, to selectively sequester the active drug.