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Edward Jenner |
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Gradually, the idea of inoculation took hold, but immunization against smallpox did not become generally accepted until the milder vaccination using cowpox virus was identified by Edward Jenner in the 1860s. The relationship between cowpox and vaccinia viruses has been unclear since Edward Jenner used a virus isolate from cows for smallpox vaccination (2,3). And in estimating a baseline mortality figure of 130,658 dead from the epidemic of 1775-82, Fenn has captured a clear sense of how catastrophic a disease like smallpox was in the days before Edward Jenner developed an effective vaccine. |
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