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enalapril
(redirected from Enalaprilat)

   Also found in: Medical, Wikipedia 0.01 sec.
enalapril [ɪˈnæləprɪl]
n
(Medicine / Pharmacology) an ACE inhibitor used to treat high blood pressure and congestive heart failure
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.enalapril - an ACE inhibitor (trade name Vasotec) that blocks the formation of angiotensin in the kidney and so results in vasodilation; administered after heart attacks
ACE inhibitor, angiotensin-converting enzyme inhibitor - an antihypertensive drug that blocks the formation of angiotensin II in the kidney, leading to relaxation of the arteries; promotes the excretion of salt and water by inhibiting the activity of the angiotensin converting enzyme; also used to treat congestive heart failure


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The role of enzyme and substrate concentration in the evaluation of serum angiotensin converting enzyme (ACE) inhibition by enalaprilat in vitro.
In a study of congestive heart failure, patients with endothelial dysfunction manifested by impaired flow-dependent, endothelium-mediated dilation, quinaprilat (having high tissue-ACE affinity) was compared with enalaprilat (which has low tissue-ACE affinity).
International pharmaceutical and health care company, F H Faulding & Co Limited (Faulding), Adelaide, South Australia, has announced that its Faulding Pharmaceuticals division has received final approval from the Food and Drug Administration (FDA) in the United States for its abbreviated new drug application (ANDA) for enalaprilat injection, following the expiry of the paediatric exclusivity period on 22 August 2000.
 
 
 
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