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endopeptidase
(redirected from Endopeptidases)

   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
en·do·pep·ti·dase  (nd-ppt-ds, -dz)
n.
Any of a large group of enzymes that catalyze the hydrolysis of peptide bonds in the interior of a polypeptide chain or protein molecule.

endopeptidase [ˌɛndəʊˈpɛptɪˌdeɪz]
n
(Life Sciences & Allied Applications / Biochemistry) any proteolytic enzyme, such as pepsin, that splits a protein into smaller peptide fragments Also called proteinase Compare exopeptidase


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The matrix metalloproteinases (MMPs) are a family of zinc- and calcium-dependent endopeptidases with a central role in inflammation and combined ability to degrade components of connective tissue matrices (Murphy and Docherty 1992).
The MMPs are zinc- and calcium-dependent endopeptidases that together can hydrolyze essentially all of the components of the extracellular matrix.
 
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