The endorphins and enkephalins
are similar to opium, heroin, and morphine, drugs derived from the seeds of the poppy plant Papaver somniferurm.
Furthermore, medical tests have revealed that massage can enhance the release of enkephalins
in the body.
are believed to have potent, opiate-like effects; thus leading to analgesia.
Chronic blockade of D2 but not D1 dopamine receptors facilitates behavioural responses to endogenous enkephalins
, protected by kelatorphan, administered in the accumbens in rats.
It's not that enkephalins
or similar drugs make the rats like the chocolates more, the researchers said, but rather that the brain chemicals increase their desire and impulse to eat them.
Dual enkephalinase inhibitors (DENKI) induce natural pain relief by inhibiting the two enzymes responsible for the rapid degradation of enkephalins
, the main endogenous opioids, thus increasing the level of these powerful physiological analgesics especially in pain-affected areas," according to Professors Bernard Roques and Marie-Claude Fournie-Zaluski, inventors of these molecules and co-founders of Pharmaleads.
As a result, in the morning there is a cascade of endogenous opiates, endorphins, and enkephalins
Curamin also contains a potent form of the anti-inflammatory herb boswellia, as well as Dl-phenylalanine (DLPA) for its ability to sustain endorphins and enkephalins
in the brain, and the enzyme nattokinase, which supports healthy circulation so that important nutrients can be better carried to the areas of need, and waste materials more efficiently removed.
These include [beta]-endorphin (which consists of 31 amino acids), dynorphin (13 amino acids), and the enkephalins
(5-amino-acid peptides that end in either methionine [met-enkephalin
] or leucine [leu-enkephalin
]) (Kandel et al.
Three main compounds, enkephalins
, GABA and endomorphins, naturally regulate pain transmission at the first order synapse.
1, ACE), acting as ectoenzymes on the outer surface of different cells and included in the metabolism of regulatory peptides, like substance P, bradykinin, enkephalins
, natriuretic peptides and other vasoactive hormonal peptides (Hooper, 1996).
Lose love and you're in withdrawal - craving all the marvellous chemicals (endorphins, enkephalins
and oxytocin) released when we're in love.