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n. Biology
Reversion of a specialized cell or tissue to an unspecialized form. Dedifferentiation may occur before the regeneration of appendages in plants and certain animals and in the development of some cancers.

de′dif·fer·en′ti·ate′ v.


(Biology) the reversion of the cells of differentiated tissue to a less specialized form


(diˌdɪf əˌrɛn ʃiˈeɪ ʃən)

n. Biol.
the loss of specialized form or condition previously acquired during development.
de`dif•fer•en′ti•ate`, v.i. -at•ed, -at•ing.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.dedifferentiation - the loss of specialization in form or function
adaption, adaptation, adjustment - the process of adapting to something (such as environmental conditions)
References in periodicals archive ?
In Germany, Eigler identifies Entdifferenzierung (a term coined by historian Peter Reichel) of GDR socialism and National Socialism and the ritualization of forms of commemoration as major tendencies.