7] Several international studies have identified OXA-181-producing Enterobacteriaceae
in the UK, the Sultanate of Oman, the Netherlands, Senegal and New Zealand.
Up to 33 percent of surveyed physicians in the EU5 countries use carbapenem-containing regimens, albeit in high doses, to treat complicated urinary tract infections due to carbapenem-resistant Enterobacteriaceae
, which is a clear indication of the lack of treatment options for these MDR pathogens.
In recent years, the rapid global spread of carbapenem-resistant Enterobacteriaceae
(CRE) has been facilitated by mobile genetic elements harboring genes encoding for carbapenemases, such as Klebsiella pneumoniae carbapenemase (KPC) and metallo-[beta]-lactamases (6,7).
Off-odor scores correlated highest with the Enterobacteriaceae
The Centers for Disease Control and Prevention named carbapenem-resistant Enterobacteriaceae
as one of the three most urgent threats among emerging forms of antibiotic-resistant disease.
For a Centers for Disease Control and Prevention toolkit on preventing carbapenem-resistant Enterobacteriaceae
infection, visit www.
The aim of this study was to gather local data on the in-vitro susceptibilities of ESBL-producing Enterobacteriaceae
from our institution, against two potentially useful oral antibiotics: fosfomycin and mecillinam, and to compare the results with other routinely tested oral agents.
Studies showed that Enterobacteriaceae
composed the vast majority of aerobic or facultatively anaerobic gram negative bacilli isolated from intra-abdominal infections, with Escherichia coli being the most commonly isolated species .
Especially with the excessive worldwide use of cephalosporins, the incidence of multidrug-resistant ESBL-producing Enterobacteriaceae
is markedly elevated (1,2).
Cronobacter sakazakii is an emerging opportunistic pathogen of the family Enterobacteriaceae
responsible for outbreaks of neonatal meningitis and necrotizing enterocolitis in the immunocompromised.
General antibiotic susceptibility was measured in the 30 isolated Enterobacteriaceae
to 11 antibiotics used in human and veterinary medicine.
The mean Enterobacteriaceae
count for vegetables ranged from 2.