fibril

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Related to Fibrils: amyloidosis, collagen fibrils

fi·bril

 (fī′brəl, fĭb′rəl)
n.
1. A small slender fiber or filament.
2. Anatomy A threadlike fiber or filament, such as a myofibril or neurofibril, that is a constituent of a cell or larger structure.
3. A long strand of proteins that are aggregated together in a beta-sheet structure; an amyloid fibril.

[New Latin fibrilla, diminutive of Latin fibra, fiber.]

fi′bril·lar (-lər), fi′bril·lar′y (-lĕr′ē) adj.
fi′bril·lose′ (-lōs′) adj.

fibril

(ˈfaɪbrɪl) or

fibrilla

n, pl -brils or -brillae (-ˈbrɪliː)
1. a small fibre or part of a fibre
2. (Biology) biology a threadlike structure, such as a root hair or a thread of muscle tissue
[C17: from New Latin fibrilla a little fibre]
ˈfibrilar, fiˈbrillar, fiˈbrillose adj
fiˈbrilliˌform adj

fi•bril

(ˈfaɪ brəl, ˈfɪb rəl)

n.
1. a small or fine fiber or threadlike structure.
[1655–65; < New Latin <fibrilla < Latin fibra fiber]
fi′bril•lar, adj.
fi′bril•lose`, adj.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.fibril - a very slender natural or synthetic fiberfibril - a very slender natural or synthetic fiber
barb - one of the parallel filaments projecting from the main shaft of a feather
cobweb, gossamer - filaments from a web that was spun by a spider
chromatid - one of two identical strands into which a chromosome splits during mitosis
myofibril, myofibrilla, sarcostyle - one of many contractile filaments that make up a striated muscle fiber
rhizoid - any of various slender filaments that function as roots in mosses and ferns and fungi etc
hypha - any of the threadlike filaments forming the mycelium of a fungus
paraphysis - a sterile simple or branched filament or hair borne among sporangia; may be pointed or clubbed
fiber, fibre - a slender and greatly elongated substance capable of being spun into yarn

fibril

noun
A very fine continuous strand:
Translations

fi·bril

n. filamento, fibrilla, fibra pequeña.
References in classic literature ?
So when in tears The love of years Is wasted like the snow, And the fine fibrils of its life By the rude wrong of instant strife Are broken at a blow Within the heart Do springs upstart Of which it doth now know, And strange, sweet dreams, Like silent streams That from new fountains overflow, With the earlier tide Of rivers glide Deep in the heart whose hope has died-- Quenching the fires its ashes hide,-- Its ashes, whence will spring and grow Sweet flowers, ere long, The rare and radiant flowers of song!
At first she would not look straight up at him, but her eyes soon lifted, and his plumbed the deepness of the ever-varying pupils, with their radiating fibrils of blue, and black, and gray, and violet, while she regarded him as Eve at her second waking might have regarded Adam.
These same proteins accumulate in thread-like deposits called amyloid fibrils in the nerve and muscle cells of patients with ALS, frontotemporal dementia (FTD) and inclusion body myopathy (IBM).
Of importance is the high interfacial bonding of the fibrils formed directly inside the matrix, which may arise from the formation of a transcrystalline layer of the matrix around the fibrils.
Their finding also supports the theory that amyloid fibrils -- strong, highly organized fibers, formed by proteins and peptides -- may have predated enzymes and triggered reactions that led to some of the earliest forms of life.
In semi-crystalline polyolefins, crystallites form aggregates, resulting in structures such as spherulites or fibrils.
The structures, called amyloid fibrils, are also implicated in neurodegenerative conditions such as Alzheimer's and Parkinson's, and in prion diseases like Creutzfeldt-Jacob and mad cow disease.
In a study that focused on the fibrils associated with AD, NatAalia Carulla and colleagues used laboratory techniques to detail molecular recycling within fibrils formed by two proteins, AB40 and AB42, which are most associated with AD.
By preventing natural GAGs from binding to the AA protein, Fibrillex is expected to prevent AA fibril formation and the deposition of AA fibrils in organs.
Because collagen makes up the fibrils that anchor the two skin layers together, Uitto's team concludes that dominant dystrophic EB results from the collagen mutation.
Also, in relevant animal models of Alzheimer's disease, the Mindset vaccine was shown to inhibit the deposition of toxic amyloid fibrils and to improve cognition.