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Freund's adjuvant

   Also found in: Medical, Wikipedia 0.07 sec.
Freund's adjuvant  (froindz)
n.
A substance consisting of killed microorganisms, such as mycobacteria, in an oil and water emulsion that is administered to induce and enhance the formation of antibodies.

[After Jules T. Freund (1890-1960), Hungarian-born American immunologist.]

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We have found in preliminary studies that the same pattern of TLR expression is induced by CB3 and the Mycobacterium in complete Freund's adjuvant, which suggests a common mechanism of activation (16).
The Company postulates that an immune-based therapy containing TCR peptides with Incomplete Freund's Adjuvant (IFA) stimulates regulatory T-cells capable of suppressing these autoreactive pathogenic T-cells.
Rabbits were immunized subcutaneously with 10 [micro]g of protein with complete Freund's adjuvant, followed by a second 10-[micro]g injection 1 month later with incomplete Freund's adjuvant and a final 10-[micro]g booster after another month.
 
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