Friedreich's ataxia

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Related to Friedreich ataxia: myotonic dystrophy
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Noun1.Friedreich's ataxia - sclerosis of the posterior and lateral columns of the spinal cord; characterized by muscular weakness and abnormal gait; occurs in children
ataxia, ataxy, dyssynergia, motor ataxia - inability to coordinate voluntary muscle movements; unsteady movements and staggering gait
References in periodicals archive ?
According to the Friedreich Ataxia Reasearch Alliance, it effects the coordination in limbs, reduces energy levels leaving a feeling of fatigue and it can lead to heart conditions and diabetes.
Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits.
Friedreich ataxia (FRDA) is the most common form of autosomal recessive ataxia.
FRDA = Friedreich ataxia AD SCA = Autosomal dominant spinocerebellar ataxia ICARS = International Cooperative Ataxia Rating Scale ADLS = Activities of Daily Living Scale DELTA - X = Right/left deviation of COP, DELTA - Y = Front/back deviation of COP, TRAJ = Absolute deviation of COP, TTW - Total traveled way during the whole test
vitamin E, N-acetylcysteine, CoQ10, idebenone) in several of these conditions--most notably, Alzheimer disease, Parkinson disease, and Friedreich ataxia.