G-CSF


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G-CSF

abbr.
granulocyte colony-stimulating factor
References in periodicals archive ?
Spectrum Pharmaceuticals In-Licenses G-CSF from Hanmi
Ancak, MTX kullanan ve pansitopeni gelisen hastalarda kemik iligi biyopsisi yapildiktan ve ikincil bir maligniteye bagli pansitopeni ekarte edildikten sonra G-CSF baslanmalidir.
The bcl3 gene, they showed, acts like a master switch to control the effects of G-CSF on neutrophil production.
Use of G-CSF primary phrophylaxis to prevent FN differed between the two groups; less than half of R-CHOP-21 patients (36%) were given G-CSF primary prophylaxis, compared to 84% of the R-CHOP-14 group and incidence of FN was 19% and 20% respectively.
Primary pulmonary squamous cell carcinoma associated with elevated IL-6, leukocytosis, hypercalcemia, phagocytosis, reactive lymphadenopathy and glomerular mesangial cell proliferation via the production of PTH-rP and G-CSF.
In the study, researchers examined the impact of G-CSF on bone development in mice.
the investigators conclude: "Treatment by G-CSF after reperfusion of infarcted myocardium could offer a pragmatic concept of potential myocardial regeneration".
In the cancer study, stem cells mobilized by Imprime PGG plus G-CSF will be harvested, reintroduced into patients following their chemotherapy, and reconstitution of their immune system monitored.
Generating large numbers of blood-producing (haematopoietic) stem cells has traditionally used G-CSF (granulocyte-colony stimulating factor) and SCF (stem cell factor).
This strategic agreement with PLIVA will further our efforts to be a leader in this emerging marketplace, and we are confident that we bring together considerable expertise that will result in the successful introduction of G-CSF and future generic biopharmaceuticals.
Cefepime induced bone marrow suppression is a possibility that resolves with its discontinuation and responds to G-CSF.
However, in this national study only about one quarter of women received G-CSF during their course of treatment--and generally not as primary prophylaxis.