glucose-6-phosphate dehydrogenase

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Related to G6PD: G6PD deficiency
Translations

glu·cose-6-phos·phate de·hy·dro·gen·ase

n. glucofosfato de deshidrogenasa, enzima presente en el hígado y los riñones necesaria en la conversión de glicerol a glucosa.
References in periodicals archive ?
Reyes said that G6PD deficiency is an x-linked inherited disorder which means that from the baby is born, there is already something wrong with how his body makes and breaks important substances.
This drug can accelerate the hemoglobin reduction process through the NADPH-dependent G6PD pathway.
It is associated with mild methaemoglobinaemia of little clinical significance, and acute haemolysis in people with G6PD deficiency.
Factors increasing serum bilirubin in newborns Increased destruction * G6PD dysfunction of red blood cells * Untreated rhesus incompatibility * ABO group incompatibility * Genetic blood cell defects * Sepsis * Birth trauma with haematoma formation Decreased plasma * Prematurity albumin concentration * Infection or illness * Competition for binding sites by drugs, eg sulphon amides, salicylates Decreased conjugation * Immature enzyme systems in liver * Genetic disorders * Inhibition by drugs eg amitriptyline, ketoconazole Increased reabsorption * Dehydration from gut * Constipation * Immature gut with poor motility * Breastfeeding
Sickle cell disease and other haemoglobin disorders such as thalassaemia and G6PD are inherited blood diseases that affect how oxygen is carried in the body.
RCC has been found to have increased activity of G6PD and trans-ketolase,[sup.
This will include measurements of total and conjugated bilirubin, urine screening, assessment for G6PD deficiency if appropriate, ensuring the Guthrie test has been performed to exclude congenital hypothyroidism, (6) and investigations to determine other possible causes.
17) He described apparent HeLa cell contamination of 19 other human cell lines by using a technique of isoenzyme analysis of glucose-6phosphate dehydrogenase (G6PD) and phosphoglucomutase (PGM) electrophoretic polymorphisms; all cell lines had the same G6PD type A and PGM type 1 phenotypes.
Newborns without G6PD deficiency also are at risk because of immature erythrocyte enzyme systems (glutathione instability).
G6PD is an enzyme that controls the rate of glucose flux via the hexose monophosphate shunt and in turn, controlling the intracellular availability of NADPH.
Therefore, enabling them to know if they are carriers of certain genetic diseases such as sickle cell disease, thalassemia and G6PD deficiency is very important," Dr Al Arrayed.