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granulocyte-macrophage colony-stimulating factor |
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| When given to chronically HIV-infected patients during an STI, GM-CSF blunted viral rebound and substantially prevented decreases in CD4 T cells in the absence of antiretroviral treatment. Researchers know these naturally occurring molecules by many acronyms, including G-CSF, GM-CSF and EPO. E75 is administered as a vaccine consisting of the peptide mixed with GM-CSF (sargramostim or Leukine([R])) as an immunoadjuvant and administered intradermally on a monthly basis for six months. |
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