GM-CSF


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Related to GM-CSF: interleukin, Cytokines, Sargramostim

GM-CSF

abbr.
granulocyte-macrophage colony-stimulating factor
References in periodicals archive ?
They found that the mice that had been given large amounts of a special cytokine - molecules that warn other cells that there's an infection or other trauma in the body - called GM-CSF, had better survival and lung function than the other mice.
In addition, it expresses GM-CSF to stimulate immune responses.
A relatively novel approach of using GM-CSF therapy in the treatment of pulmonary alveolar proteinosis in humans is being studied after murine studies showed resolution of a PAP-like syndrome in mice with GM-CSF deficiency on administration of local GM-CSF therapy.
2015;33:2780-8), patients with injectable melanoma that was not surgically resectable were randomized to either intralesional T-VEC injections on week 0, 3, and then every 2 weeks (295 patients), or subcutaneous GM-CSF 125 meg/[m.
Administration of GM-CSF is controversial, as antibodies against GM-CSF are absent [14]; however, in severe cases, it may be reasonable to give this drug while awaiting anti-GM-CSF serologic test results.
Researchers discovered that GM-CSF producing B cells were more frequent and more prone to activation in MS patients.
sup][10] GM-CSF followed by WLL could be attempted; the response rate to this combination in one study varied from 43% to 92%, and the relapse rate in GM-CSF responders was 29.
The role of GM-CSF in autoimmune and inflammatory disorders makes it of interest for assessment in vitiligo.
Kingfisher Biotech's mouse GM-CSF protein has been shown to be a superior product for use in cell culture.
However, a measurement of GM-CSF level by immunoassay in pleural fluid in patients with lung cancer is valuable (1).
1992), where different concentrations of IL-4 and GM-CSF were used for optimal growth and biological response (Lardon et al.
E75 is a nine-amino acid sequence that is immunogenic (produces an immune response) and GM-CSF is a commercially available protein that acts to stimulate and activate components of the immune system such as macrophages and dendritic cells.