It was lucky that some tins of fine preserves were stowed in a locker in my stateroom; hard bread I could always get hold of; and so he lived on stewed chicken, PATE DE FOIE GRAS
, aspara- gus, cooked oysters, sardines--on all sorts of abominable sham delicacies out of tins.
criteria require that the safe use of ingredients in human and animal food be widely recognized by the appropriate qualified experts.
A 2010 Government Accountability Office report recommended that the FDA increase its supervision of the GRAS
system and "'minimize the potential for conflicts of interest in companies' GRAS
The FDA has issued a 'no objection letter' to the GRAS
petition for PinnoThin[R], confirming its 'GRAS
' status in applications.
3) The definitions highlighted above clearly distinguish a food additive from a GRAS
status can be based either upon common use in food prior to 1958 or upon "scientific procedures," for example, toxicological studies or other scientific information.
If new evidence suggests that a GRAS
or prior-sanctioned substance, may be unsafe, federal authorities can prohibit its use or require further studies to determine its safety.
The Flavor Extracts Manufacturers Association (FEMA), for example, also has an expert panel to determine the GRAS
status of artificial flavors made from natural products.
There are two approaches to achieve GRAS
status, based on 1) history of safe use and 2) scientific procedures, or both, which are discussed in more detail here.
is an acronym for the phrase "Generally Recognized As Safe".
The wording of the 1958 amendment seems a bit turned on its head (that is, a food additive unless GRAS
), but Congress was trying to make the point that approval by the GRAS
process was an exception to the rule that all substances should be reviewed by the FDA.
If a substance qualifies as GRAS
when added to food in a particular application, there is no need to obtain any type of clearance or pre-market authorization from FDA before it is used.