general paralysis of the insane(redirected from General paresis of the insane)
Also found in: Medical, Encyclopedia, Wikipedia.
general paralysis of the insane
(Pathology) a disease of the central nervous system: a late manifestation of syphilis, often occurring up to 15 years after the original infection, characterized by mental deterioration, speech defects, and progressive paralysis. Abbreviation: GPI Also called: general paresis or dementia paralytica