BRCA1

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Related to Genes, brca1: BRCA2 gene

BRCA1

n.
A gene that is associated with the development of familial breast cancer when inherited in a defective state.

[br(east) ca(ncer) 1.]
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References in periodicals archive ?
Not only that, these cancer genes, BRCA1 and BRCA2, besides causing breast cancer are also implicated in ovarian cancer, and prostate cancer too.
The primary purpose of the study was to estimate the risk of cancer associated with having three specific alterations in the breast cancer genes, BRCA1 and BRCA2.
Women with harmful mutations in either of two genes, BRCA1 and BRCA2, have a risk of breast cancer that is about five times the normal risk, and a risk of ovarian cancer that is about ten to thirty times normal.
The lawsuit challenges the validity of patents on two hereditary breast and ovarian cancer genes, BRCA1 andBRCA2.
Laboratory experiments already suggest that cells with faulty RAD51D are sensitive to PARP inhibitors - a new class of drugs designed to target cancers caused by faults in two known breast and ovarian cancer genes, BRCA1 and BRCA2.
Desde 1995, una gran proporcion de casos hereditarios son atribuibles a mutaciones en dos genes, BRCA1 y BRCA2 (107).
Washington, DC) notes the progress made in genetic counseling relating to the disease since the cloning in the mid-1990's of the breast cancer susceptibility genes, BRCA1 and BRCA2.
Genetic testing is available for the major breast and ovarian cancer predisposing genes, BRCA1 and BRCA2.
Mutations in these genes, BRCA1 or BRCA2, are responsible for around 2,200 of the 44,000 cases of breast cancer diagnosed annually in the UK.
By 1990, the group had significantly narrowed down the location of one of the key genes, BRCA1.
Approximately 5-10% of breast cancer cases ate the result of inherited mutations, or alterations in breast cancer susceptibility genes, BRCA1 and BRCA2.