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germ line
(redirected from Germline)

   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
germ line
n
(Life Sciences & Allied Applications / Genetics) the lineage of cells culminating in the germ cells


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This type of therapy actually involves replacing genes in germline, which will be translated to the next generation," said Mitalipov.
The researchers were surprised to notice a difference between the genome structure in the germline - the cells that become eggs and the sperm that fertilize them - and the genome structure in the resulting embryonic cells.
In the technique developed at Newcastle, stem cells with XY chromosomes (male) were developed into germline stem cells which were then prompted to complete meiosis - cell division with halving of the chromosome set.
 
 
 
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