macrophage

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mac·ro·phage

 (măk′rə-fāj′)
n.
Any of various large, phagocytic white blood cells that develop from monocytes, are found in the spleen, liver, and other tissues, and have a variety of functions in the immune system including engulfing and destroying pathogens and dead cells, presenting antigens to activate lymphocytes, and releasing cytokines that mediate inflammation.


mac′ro·phag′ic (-făj′ĭk) adj.

macrophage

(ˈmækrəʊˌfeɪdʒ)
n
(Zoology) any large phagocytic cell occurring in the blood, lymph, and connective tissue of vertebrates. See also histiocyte
macrophagic adj

mac•ro•phage

(ˈmæk rəˌfeɪdʒ)

n.
a large white blood cell, occurring principally in connective tissue and in the bloodstream, that ingests foreign particles and infectious microorganisms by phagocytosis.
[< German Makrophagen (pl.) (Metchnikoff, 1887), with -phagen representing Phagozyten phagocytes; see macro-, -phage]
mac`ro•phag′ic (-ˈfædʒ ɪk) adj.

mac·ro·phage

(măk′rə-fāj′)
Any of the large white blood cells in many vertebrates that engulf and break down foreign particles and bacteria in blood or lymph. Macrophages are important in the body's defense against disease and are found mainly in the spleen, lymph nodes, and liver.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.macrophage - a large phagocytemacrophage - a large phagocyte; some are fixed and other circulate in the blood stream
histiocyte - a macrophage that is found in connective tissue
phagocyte, scavenger cell - a cell that engulfs and digests debris and invading microorganisms
Translations
makrofág
FresszelleMakrophage
マクロファージ
makrofag

mac·ro·phage

n. macrófago, célula mononuclear fagocítica;
___ migrationmigración de ___ -s.
References in periodicals archive ?
In the current case, no giant cells were visualized.
1,2) The definitive diagnostic test is a temporal artery biopsy that shows granulomatous arteritis with giant cells and destruction of the elastic lamina.
Histologic examination of the cerebrum and spinal cord revealed multiple adult filarial nematodes surrounded by granulomatous inflammation with several multinucleated giant cells.
There was no fibrinoid necrosis, leukocytoclasia or giant cells in the examined biopsy specimen.
Histologic examination reveals inflammation in breast lobules and noncaseating granulomas containing clustered epitheloid histiocytes, lymphocytes, plasma cells, neutrophils, and giant cells (3).
Histopathology revealed multiple blood-filled cystic spaces with adjoining cellular spindle shaped fibroblastic proliferation interspersed by multinucleate giant cells, hemosiderin laden macrophages.
Microscopically, the masses showed classic features of TSGCT and composed of multinucleated giant cells, xanthoma cells, mononuclear cells, and stromal cells [Figure 1]f.
Microscopical examination showed sheets of round to oval mononuclear cells with bland chromatin and conspicuous nucleoli uniformly interspersed with numerous osteoclast-like giant cells with nuclei similar to that of the mononuclear cells confirming the histopathological diagnosis of giant cell tumor [Figure 3].
Standard sections revealed a cellular process including giant cells and mononuclear stromal cells within a collagenous matrix (Figure 3(a)).
Hematoxylin and eosin stain histological slide demonstrates characteristic giant cells (Figure 11).
Multinucleated giant cells were present in a scattered manner, diffusely throughout the lesion.
Neoplastic multinucleated giant cells are common, and reactive foreign-body-type giant cells may also be seen (figure 2).