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thrombasthenia
(redirected from Glanzmann thrombasthenia)

    Also found in: Medical, Wikipedia 0.02 sec.
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Noun1.thrombasthenia - a rare autosomal recessive disease in which the platelets do not produce clots in the normal way and hemorrhage results
autosomal recessive defect, autosomal recessive disease - a disease caused by the presence of two recessive mutant genes on an autosome
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For example, Glanzmann thrombasthenia is a deficiency of the IIb and/or IIIa subunits of the GP IIb/IIIa receptor.
Genetic polymorphisms associated with venous and arterial thrombosis; ... by Kottke-Marchant, Kandice / Archives of Pathology & Laboratory Medicine
Intensive and Successful Transfusion of Pathogen Inactivated INTERCEPT Platelet Concentrates for Major Gynecological and Obstetrical Surgery in Glanzmann Thrombasthenia Type 1 with Gypsy Mutation documented the ability of INTERCEPT-treated platelets to support two patients with a recessive autosomal severe bleeding disorder during surgical procedures.
Cerus Announces INTERCEPT Blood System Data Presented at ... by Business Wire
It has been used to detect the absence of glycoprotein IIb/IIIa receptors in patients with Glanzmann thrombasthenia and has been used to study deficiencies of glycoprotein Ia, Ib, IIb, IV, and IX.
The laboratory diagnosis of platelet disorders: an algorithmic ... by Kottke-Marchant, Kandice; Corcoran, George / Archives of Pathology & Laboratory Medicine
 
 
 
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