ACLS

(redirected from Gli3)
Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.

ACLS

abbr.
advanced cardiac life support
Translations

ACLS

abbr advanced cardiac life support. V. support.
Mentioned in ?
References in periodicals archive ?
Upon activation of HH signaling by binding of 1 of the 3 mammalian HH proteins (sonic hedgehog, Indian hedgehog, desert hedgehog) to PTCH, SMO is released and then activates interacting proteins such as suppressor of fused (SUFU), ultimately leading to activation of Gli (Gli family zinc finger) transcription factors Glil, Gli2, and Gli3, whose function is controlled by phosphorylation and proteolytic degradation (Figure 2).
Buscher D, Bosse B, Heymer J, Ruther U (1997) Evidence for genetic control of Sonic hedgehog by Gli3 in mouse limb development.
Mutations or deletions in GLI3 at the 7p13 locus have been shown to cause GCPS (1,2,3).