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glomerular |
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| The second layer is the glomerular basement membrane (GBM) which is a filtration barrier by virtue of negative charge. heparanase is a critical factor in maintaining the integrity of glomerular basement membrane seen in such conditions as diabetic nephropathy, contributes to tumor cell invasion and angiogenesis. Donaghy M, Rees AJ: Cigarette smoking and lung hemorrhage in glomerulonephritis caused by autoantibodies to glomerular basement membrane. |
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