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Related to Glutamic acid decarboxylase: Glutamic Acid Decarboxylase Antibody, GAD65


 (dē′kär-bŏk′sə-lās′, -lāz′)
Any of various enzymes that catalyze the elimination of a carboxyl group, usually by hydrolysis.


(Biochemistry) an enzyme that catalyses the removal of carbon dioxide from a compound
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.decarboxylase - any of the enzymes that hydrolize the carboxyl group
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
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5%) tested positive for glutamic acid decarboxylase autoantibodies compared to 15(25%) in type 2 diabetics, 6(15%) among relatives of type 1, 7(11.
3] Nonstandard abbreviations: IAA, insulin autoantibody; GAD65, glutamic acid decarboxylase, 65-kDa isoform; IA-2, insulinoma-associated antigen 2; ZnT8, zinc transporter 8; DASP, Diabetes Antibody Standardization Program; NIR-FE, near-infrared fluorescence-enhanced; PEG, polyethyleneglycol; Cy, cyanine.
Pyridoxal phosphate in turn stimulates the activity of glutamic acid decarboxylase which catalyzes GABA synthesis.
Autoantibodies to glutamic acid decarboxylase in a patient with stiff-man syndrome, epilepsy, and type I diabetes mellitus.
The target genes were uidA, tnaA, gadA/B and cadA encoding for [beta]-D-glucuronidase, tryptophanase, glutamic acid decarboxylase and lysine decarboxylase, respectively.
Glutamic acid decarboxylase (GAD) and y-aminobutyric acid transaminase (GABA-T) are the GABA synthesizing and metabolizing enzymes, respectively (Sherif and Ahmed 1995).
This study was to investigate the change in two forms of glutamic acid decarboxylase (GABA synthesized enzymes) GADgs and GA[D.
Another striking finding in our case was the presence of Anti Glutamic Acid decarboxylase antibody which is never described in conjunction with PHP.
However, glutamic acid decarboxylase (GAD) gene therapy is not the only type of gene therapy under investigation for Parkinson's disease.
Kaplitt used the virus to deliver glutamic acid decarboxylase (GAD), the enzyme that synthesizes the neurotransmitter GABA.
The deal, which is for development and commercialisation of glutamic acid decarboxylase (GAD)-based therapy Diamyd for the treatment and prevention of type 1 diabetes, was announced on 22 June 2010 and approved by the US competition authorities earlier this month.

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