The cytoplasm of acinar cells was filled with mitochondria, rough endoplasmic reticulum and Golgi complex
Finally, ATF6 is activated in the Golgi complex
through proteolytic cleavage and translocates to nucleus where it cooperates with XBP1 in upregulation of chaperones and ERAD-related genes .
Free ribosomes and hypertrophied golgi complex
were also observed in the cytoplasm.
EE cells have a more distinct Golgi complex
than other endothelial cells in blood vessels of the heart.
Part I focuses on proteins, including the Atg5-12 families, ubiquitin, p62, and the Golgi complex
and autophagosomes in protein secretion.
Clusters of mitochondria and Golgi complex
were observed with peripheral distribution (Figure 1).
An acrosome vesicle, derived from the Golgi complex
, was observed near the nuclear envelope (Fig.
In SKM cells, the canonical ER distribution is not clear: cells may contain two major rough ER subcompartments, one without exit sites, localized in correspondence to the I-band, and a second responsible for export activity toward the Golgi Complex
(GC), near the Z-disc.
Under transmission electron microscope, the ultrastructure of treated cells were not clearly distinguishable, the membranes of the mitochondrion, RER, Golgi complex
were broken or loosened, and the endoplasmic reticulum (ER) was degranulated.
Key words that apply are organelles, secretion, enzymes, hormones, ribosomes, endoplasmic reticulum, Golgi complex
, vesicle, and plasma membrane.
2E), but neither Golgi complex
nor rough endoplasmic reticulum is observed to be present.
We obtained samples from patients with known glycosylation defects associated with the proteins that are encoded by these genes: mannosyl ([alpha]-1,6-)-glycoprotein [beta]-1,2-N-acetylglucosaminyltransferase (MGAT2); [beta]-1,4-galactosyltransferase 1 (B4GALT1); solute carrier family 35 (CMP-sialic acid transporter), member A1 (SLC35A1; other designation: CMP-sialic acid transporter); solute carrier family 35, member C1 (SLC35C1; other designation: GDP-fucose transporter); component of oligomeric Golgi complex
7 (COG7); and ATPase, H+ transporting, lysosomal V0 subunit a2 (ATP6V0A2).