growth cone


Also found in: Thesaurus, Medical, Legal, Financial, Encyclopedia, Wikipedia.

growth′ cone`


n.
a flattened neuronal area, at the ends of growing axons and dendrites, having radiating structures that guide the pathways of embryonic nerve fibers.
References in periodicals archive ?
If conditions are favorable, the retraction bulb is transformed in a growth cone, a dynamic structure, which extends and guides the regenerating axon towards its target.
At the end of each neurite is a growth cone where structural proteins are assembled to form the cell membrane.
The team found that RNA molecules embedded in the growth cone are responsible for instructing the axon to move left or right, up or down.
Adhesion to the structures with which the growth cone contacts also plays a role.
Neurons were plated between grooves scored onto the cell culture dish to restrict neurite outgrowth and facilitate growth cone interactions with muscle fibers (Fig.
Their topics include investigating systems to study the biological effects of weak physiological electrical fields, stem cell physiological responses to noninvasive electrical stimulation, how physiological electric fields can direct keratinocyte migration and promote healing in chronic wounds, inflammatory cell electrotaxis, neuronal growth cone guidance by physiological direct current electric fields, and whether applied voltages can be used to produce spinal cord regeneration and recover in humans.
Actions of cytochalasins on the organization of actin filaments and microtubules in a neuronal growth cone.
Other topics include quantum dots as cellular probes, microfluidic and microfabricated devices for blood cell separation, growth cone and axonal pathfinding strategies, the mechanics of healing myocardial infarcts, and functional electrical stimulation for neuromuscular applications.
The trkA receptor mediates growth cone turning toward a localized source of nerve growth factor.
The growth cone is able to move through the environment, sensing structural and chemical cues and laying down the new axon (Fig 1).
Particularly important are the molecules that attract or repel the growth cone.
The next section focuses on the policy debate in 1960 and Bryan's introduction of a short-term, reserve growth cone as an operating guide.