receptor

(redirected from H3 receptor)
Also found in: Thesaurus, Medical, Legal, Encyclopedia.
Related to H3 receptor: H1 receptor, H2 receptor, H3 receptor antagonists

re·cep·tor

 (rĭ-sĕp′tər)
n.
1. Physiology A specialized cell or group of nerve endings that responds to sensory stimuli.
2. Biochemistry A molecular structure or site on the surface or interior of a cell that binds with substances such as hormones, antigens, or neurotransmitters or is activated by events such as a change in the concentration of an ion.

receptor

(rɪˈsɛptə)
n
1. (Physiology) physiol a sensory nerve ending that changes specific stimuli into nerve impulses
2. any of various devices that receive information, signals, etc

re•cep•tor

(rɪˈsɛp tər)

n.
1. a protein molecule, usu. on the surface of a cell, that is capable of binding to a complementary molecule, as a hormone, antibody, or antigen.
2. a sensory nerve ending or sense organ that is sensitive to stimuli.
[1900–05]

re·cep·tor

(rĭ-sĕp′tər)
1. A nerve ending specialized to sense or receive stimuli. Skin receptors respond to stimuli such as touch and pressure and signal the brain by activating portions of the nervous system. Receptors in the nose detect odors.
2. A cell structure or site that is capable of combining with a hormone, antigen, or other chemical substance.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.receptor - a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological responsereceptor - a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
anatomical structure, bodily structure, body structure, complex body part, structure - a particular complex anatomical part of a living thing; "he has good bone structure"
alpha receptor, alpha-adrenergic receptor, alpha-adrenoceptor - receptors postulated to exist on nerve cell membranes of the sympathetic nervous system in order to explain the specificity of certain agents that affect only some sympathetic activities (such as vasoconstriction and relaxation of intestinal muscles and contraction of smooth muscles)
beta receptor, beta-adrenergic receptor, beta-adrenoceptor - receptors postulated to exist on nerve cell membranes of the sympathetic nervous system in order to explain the specificity of certain agents that affect only some sympathetic activities (such as vasodilation and increased heart beat)
2.receptor - an organ having nerve endings (in the skin or viscera or eye or ear or nose or mouth) that respond to stimulationreceptor - an organ having nerve endings (in the skin or viscera or eye or ear or nose or mouth) that respond to stimulation
lateral line, lateral line organ - sense organs of fish and amphibians; believed to detect pressure changes in the water
organ - a fully differentiated structural and functional unit in an animal that is specialized for some particular function
enteroceptor, interoceptor - any receptor that responds to stimuli inside the body
exteroceptor - any receptor that responds to stimuli outside the body
pineal eye, third eye - a sensory structure capable of light reception located on the dorsal side of the diencephalon in various reptiles
baroreceptor - a sensory receptor that responds to pressure
chemoreceptor - a sensory receptor that responds to chemical stimuli
thermoreceptor - a sensory receptor that responds to heat and cold
eye, oculus, optic - the organ of sight
ear - the sense organ for hearing and equilibrium
organ of hearing - the part of the ear that is responsible for sensations of sound
inner ear, internal ear, labyrinth - a complex system of interconnecting cavities; concerned with hearing and equilibrium
semicircular canal - one of three tube loops filled with fluid and in planes nearly at right angles with one another; concerned with equilibrium
stretch receptor - a receptor in a muscle that responds to stretching of the muscle tissue
papilla - a small nipple-shaped protuberance concerned with taste, touch, or smell; "the papillae of the tongue"
sensory system - the body's system of sense organs
effector - an organ (a gland or muscle) that becomes active in response to nerve impulses
Translations

receptor

[rɪˈseptəʳ] N (Physiol, Rad) → receptor m

receptor

[rɪˈsɛptər] n (ANATOMY)récepteur m

receptor

n
(= nerve)Reizempfänger m, → Rezeptor m
(Rad) → Empfänger m

receptor

[rɪˈsɛptəʳ] nrecettore m

re·cep·tor

n. receptor, terminación nerviosa que recibe un estímulo y lo transmite a otros nervios;
auditory ______ auditivo;
contact ______ de contacto;
mechanoreceptormecanoreceptor;
chemoreceptorquimoreceptor;
proprioceptive ______ propioceptivo;
sensory ______ sensorial;
taste ______ gustativo;
temperature ______ de temperatura.

receptor

n receptor m; estrogen receptor-positive positivo para receptores de estrógeno
References in periodicals archive ?
The pipeline is completed by a histamine H3 receptor antagonist program possessing CNS-sparing properties which is in advanced preclinical development and an early-stage spleen tyrosine kinase (SYK) inhibitor program suitable for topical administration.
Furthermore, preclinical and clinical studies are currently investigating the potential use of the H3 receptor antagonists for the treatment of cognitive disorders such as Alzheimer's disease (6,7).
Related conclusions come from an independentstudy by researchers at the University of Cincinnati's College of Medicine, who found the H3 receptor on nerve endings that surround blood vessels.
Ziarco's pipeline includes a histamine H4 receptor antagonist programme, with a lead compound that has completed a Phase 1 multiple ascending dose study; a clinical stage cytosolic phosholipase A2 (cPLA2) inhibitor; histamine H3 receptor antagonists possessing CNS-sparing properties, with a lead compound in advanced preclinical development; as well as early-stage spleen tyrosine kinase (SYK) inhibitor molecules suitable for topical administration.
4) Centrally Acting Drugs 4a) Compounds Predominantly Modulating Local Availability of Dopamine, Norepinephrine and Serotonin in the Brain 4b) MC4R (Melanocortin 4 Receptor) Agonists and MCH-R1 (Melanin-Concentrating Hormone Receptor 1) Antagonists 4c) H3 Receptor Antagonists 4d) Neuropeptide Y (NPY) Receptor Antagonists & Agouti-Related Protein (AgRP) Inhibitors
Nasdaq: ARNA) announced today the initiation of patient screening in a Phase 1 clinical trial of APD916, a novel oral drug candidate discovered by Arena that targets the histamine H3 receptor for the treatment of narcolepsy and cataplexy.
The H3 receptor is a target for the potential treatment of sleep disorders, attention deficit hyperactivity disorder (ADHD), and cognitive deficits (e.