In this model, every 10-mg/dL increment in baseline HDL cholesterol
correlated with a 21% drop in incident cancers, Dr.
The principal endpoint is the change in HDL cholesterol
measured after the six-month booster.
In a related finding, a 3-year investigation of 875 postmenopausal women revealed that those who took either estrogen alone or estrogen combined with a naturally derived form of progesterone had greater increases in HDL cholesterol
than those taking a placebo or those taking estrogen with a common synthetic progesterone.
The lipid management and control is effected through a two pronged attack - first reducing LDL and total cholesterol using Statins, and the other is to increase the HDL Cholesterol
using Niacin etc.
MIAMI BEACH -- Male physicians who decreased or maintained a low body mass index and/or started or continued to drink an average of one or more alcohol drinks per day experienced small but significant improvements in their HDL cholesterol
levels at 14 years' follow-up, according to a study.
The benefit comes when soy protein is added daily to dietary intake because "it increases protective HDL cholesterol
," the publication reported.
Cardiologists urge their patients to exercise and eat healthful foods in order to lower LDL and raise HDL cholesterol
counts, thereby reducing the risk of heart disease.
Goodman highlights that every 1% increase in HDL can significantly enhance support of heart health, "Now that patients require the added benefits of increasing HDL levels, it is critical to ensure that increasing HDL cholesterol
is done safely.
He presented data from a multicenter, double-blind, phase II, dose-ranging study involving 493 patients with elevated LDL cholesterol in which torcetrapib 60 mg/day plus atorvastatin 10-80 mg/day--the doses in clinical development--resulted in dose-dependent 44%-66% increases in cardioprotective HDL cholesterol
, along with LDL cholesterol reductions of 41%-60%.
Food and Drug Administration ("FDA") for a treatment indication for increasing HDL cholesterol
(commonly referred to as "good cholesterol") in patients with dyslipidemia.
For example, the new guidelines stilt mark LDL as the primary target of cholesterol-lowering therapy, but they urge physicians to determine the amount of HDL cholesterol
in patients' blood, even labeling it a "negative risk factor" for heart disease.
Previous outcomes studies have shown that niacin has proven efficacy in reducing cardiovascular events and favorable effects on HDL cholesterol
and triglyceride levels.